{"product_id":"9783032448149","title":"Sodium Glucose Transporter 2 Inhibitors","description":"\u003ch3\u003eHandbook of Experimental Pharmacology\u003c\/h3\u003e\u003ch1\u003eSodium Glucose Transporter 2 Inhibitors\u003c\/h1\u003e\u003ch3\u003eMartin C. Michel | Volker Vallon\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\u003cp\u003eInhibitors of the sodium glucose transporter 2 (SGLT2) such as canagliflozin, dapagliflozin, or empagliflozin were primarily developed for the treatment of diabetes. Meanwhile, they have been game changers in the treatment of conditions such as heart failure and renal failure in both diabetic and non-diabetic patients. Importantly, they do not only improve disease-specific outcomes but even reduce overall mortality by about one third. Thus, they have become game changers for indications affecting millions of people. This volume discusses their efficacy and safety with emphasis on diabetes, heart failure and renal failure. Mechanistic insight from animal studies and potential additional uses are also being discussed.\u003c\/p\u003e\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e13 May 2027\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eSpringer Nature Switzerland\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783032448149\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Springer Nature Switzerland","offers":[{"title":"Default Title","offer_id":63036467216524,"sku":"9783032448149","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783032448149.tif?v=1792190211","url":"https:\/\/lateknightbooks.com\/products\/9783032448149","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}