This volume constitutes the refereed proceedings of the Second International Conference on Innovative Perspectives on Computational Intelligence and Data Science, InnoComp 2026, held in Lisbon, Portugal, during November 9–11, 2026.

The 54 full papers presented in this volume were carefully selected and reviewed from 105 submissions. The papers cover a broad range of topics that include Computational Intelligence, Data Science, Intelligent Systems, Applications, and Workshops on Computational Intelligence and Resilient Digital Services for Trustworthy Cyber Ecosystems.