{"product_id":"9783319079103","title":"Current Topics in Microbiology and Immunology","description":"\u003ch1\u003eCurrent Topics in Microbiology and Immunology\u003c\/h1\u003e \u003ch2\u003eDaeron, Marc; Nimmerjahn, Falk\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, \u003ci\u003eOld and New FcRs\u003c\/i\u003e, deals with the long-sought-after FcµR and the recently discovered FCRL family and TRIM21. Part II, \u003ci\u003eFcR Signaling\u003c\/i\u003e, presents a computational model of FcεRI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, \u003ci\u003eFcR Biology\u003c\/i\u003e, addresses major physiological functions of FcRs, their glycosylation, how they induce and regulate both adaptive immune responses and inflammation, especially in vivo, FcR humanized mice, and the multifaceted properties of FcRn. Part IV, \u003ci\u003eFcRs and Disease\u003c\/i\u003e, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection. In Part V, \u003ci\u003eFcRs and Therapeutic Antibodies\u003c\/i\u003e, the roles of various FcRs, including FcγRIIB and FcαRI, in the immunotherapy of cancer and autoimmune diseases using monoclonal antibodies and IVIg are highlighted. All 18 chapters were written by respected experts in their fields, offering an invaluable reference source for scientists and clinicians interested in FcRs and how to better master antibodies for therapeutic purposes.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2014-08-25\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319079103\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-07911-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 424\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":50089765109900,"sku":"9783319079103","price":179.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319079103.jpg?v=1779503004","url":"https:\/\/lateknightbooks.com\/products\/9783319079103","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}