{"product_id":"9783319237237","title":"Computational Biology: From Live Imaging to Knowledge","description":"\u003ch1\u003eComputational Biology: From Live Imaging to Knowledge\u003c\/h1\u003e \u003ch2\u003eBhanu, Bir; Talbot, Prue\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cdiv\u003eThe advances of live cell video imaging and high-throughput technologies for functional and chemical genomics provide unprecedented opportunities to understand how biological processes work in subcellular\u003c\/div\u003e\u003cdiv\u003eand multicellular systems. The interdisciplinary research field of Video Bioinformatics is defined by Bir\u003c\/div\u003e\u003cdiv\u003eBhanu as the automated processing, analysis, understanding, data mining, visualization, query-based\u003c\/div\u003e\u003cdiv\u003eretrieval\/storage of biological spatiotemporal events\/data and knowledge extracted from dynamic images\u003c\/div\u003e\u003cdiv\u003eand microscopic videos. Video bioinformatics attempts to provide a deeper understanding of continuous\u003c\/div\u003e\u003cdiv\u003eand dynamic life processes.\u003c\/div\u003e\u003cdiv\u003eGenome sequences alone lack spatial and temporal information, and video imaging of specific molecules\u003c\/div\u003e\u003cdiv\u003eand their spatiotemporal interactions, using a range of imaging methods, are essential to understand\u003c\/div\u003e\u003cdiv\u003ehow genomes create cells, how cells constitute organisms, and how errant cells cause disease. The book\u003c\/div\u003e\u003cdiv\u003eexamines interdisciplinary research issues and challenges with examples that deal with organismal dynamics,\u003c\/div\u003e\u003cdiv\u003eintercellular and tissue dynamics, intracellular dynamics, protein movement, cell signaling and software\u003c\/div\u003e\u003cdiv\u003eand databases for video bioinformatics.\u003c\/div\u003e\u003cdiv\u003eTopics and Features\u003c\/div\u003e\u003cdiv\u003e• Covers a set of biological problems, their significance, live-imaging experiments, theory and\u003c\/div\u003e\u003cdiv\u003ecomputational methods, quantifiable experimental results and discussion of results.\u003c\/div\u003e\u003cdiv\u003e• Provides automated methods for analyzing mild traumatic brain injury over time, identifying injury\u003c\/div\u003e\u003cdiv\u003edynamics after neonatal hypoxia-ischemia and visualizing cortical tissue changes during seizure\u003c\/div\u003e\u003cdiv\u003eactivity as examples of organismal dynamics\u003c\/div\u003e\u003cdiv\u003e• Describes techniques for quantifying the dynamics of human embryonic stem cells with examples\u003c\/div\u003e\u003cdiv\u003eof cell detection\/segmentation, spreading and other dynamic behaviors which are important for\u003c\/div\u003e\u003cdiv\u003echaracterizing stem cell health\u003c\/div\u003e\u003cdiv\u003e• Examines and quantifies dynamic processes in plant and fungal systems such as cell trafficking,\u003c\/div\u003e\u003cdiv\u003egrowth of pollen tubes in model systems such as Neurospora Crassa and Arabidopsis\u003c\/div\u003e\u003cdiv\u003e• Discusses the dynamics of intracellular molecules for DNA repair and the regulation of cofilin\u003c\/div\u003e\u003cdiv\u003etransport using video analysis\u003c\/div\u003e\u003cdiv\u003e• Discusses software, system and database aspects of video bioinformatics by providing examples of\u003c\/div\u003e\u003cdiv\u003e5D cell tracking by FARSIGHT open source toolkit, a survey on available databases and software,\u003c\/div\u003e\u003cdiv\u003ebiological processes for non-verbal communications and identification and retrieval of moth images\u003c\/div\u003e\u003cdiv\u003eThis unique text will be of great interest to researchers and graduate students of Electrical Engineering,\u003c\/div\u003e\u003cdiv\u003eComputer Science, Bioengineering, Cell Biology, Toxicology, Genetics, Genomics, Bioinformatics, Computer\u003c\/div\u003e\u003cdiv\u003eVision andPattern Recognition, Medical Image Analysis, and Cell Molecular and Developmental Biology.\u003c\/div\u003e\u003cdiv\u003eThe large number of example applications will also appeal to application scientists and engineers.\u003c\/div\u003e\u003cdiv\u003eDr. Bir Bhanu is Distinguished Professor of Electrical \u0026amp; C omputer Engineering, Interim Chair of the\u003c\/div\u003e\u003cdiv\u003eDepartment of Bioengineering, Cooperative Professor of Computer Science \u0026amp; Engineering, and Mechanical\u003c\/div\u003e\u003cdiv\u003eEngineering and the Director of the Center for Research in Intelligent Systems, at the University of California,\u003c\/div\u003e\u003cdiv\u003eRiverside, California, USA.\u003c\/div\u003e\u003cdiv\u003eDr. Prue Talbot is Professor of Cell Biology \u0026amp; Neuroscience and Director of the Stem Cell Center and Core at\u003c\/div\u003e\u003cdiv\u003ethe University of California Riverside, California, USA.\u003c\/div\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2015-12-23\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319237237\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-23724-4\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 381\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":47661703463052,"sku":"9783319237237","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319237237.jpg?v=1776433463","url":"https:\/\/lateknightbooks.com\/products\/9783319237237","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}