Gilles Courtois (INSERM) and colleagues are performing genetic research at the Institut des Neurosciences de Grenoble. They have demonstrated details of the NF-kB signaling pathway and collaborate on publications about Incontinentia Pigmenti, a genetic disease of the skin, hair, teeth and central nervous system. He and his team are working with the group of Annie Andrieux and Eric Denarier on mice lacking the NEMO protein, one component of the signal cascade, exclusively in their nervous system or throughout their body. The studies focus on neurological problems but will provide insight into the signaling pathway from different angles.