{"product_id":"9783319331706","title":"Progress in the Chemistry of Organic Natural Products","description":"\u003ch1\u003eProgress in the Chemistry of Organic Natural Products\u003c\/h1\u003e \u003ch2\u003eKinghorn, A. Douglas; Falk, Heinz; Gibbons, Simon; Kobayashi, Jun'ichi\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe first contribution reviews the phytochemical, chemical,\nand biological literature on members of the ingenane class of diterpenoids from\ntheir first isolation in 1968 through 2015, highlighting unresolved issues both\ncommon to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the\nlight of the Jakupovic proposal of a dissection between the formation of the macrocyclic\n\u003ci\u003eEuphorbia\u003c\/i\u003e diterpenoids and the phorboids,\nand the clinical development of ingenol mebutate is chronicled in the light of\nits “reverse-pharmacology” focus.\u003cbr\u003eThe second contribution\noffers a comprehensive view of the chemical wealth and the taxonomic problems\ncurrently impeding chemical and biological investigations of the genus \u003ci\u003eLaurencia\u003c\/i\u003e. It addresses the botanical description and the growth and\npopulation dynamics of the genus, as well as its chemical diversity and ecological\nrelations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-07-15\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319331706\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-33172-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 252\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":45587078840460,"sku":"9783319331706","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319331706_ef334a11-b3b7-4fe8-9677-83ea47d6b54f.jpg?v=1772925518","url":"https:\/\/lateknightbooks.com\/products\/9783319331706","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}