{"product_id":"9783319459486","title":"The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease: Cushing’s Syndrome and Beyond","description":"\u003ch1\u003eThe Hypothalamic-Pituitary-Adrenal Axis in Health and Disease: Cushing’s Syndrome and Beyond\u003c\/h1\u003e \u003ch2\u003eGeer, Eliza B.\u003c\/h2\u003e \u003cp\u003eCushing´s  syndrome is a rare disorder that is associated with many co-morbidities  such as systemic hypertension, diabetes, osteoporosis, impaired immune  function, and psychiatric disease, all  of which severely reduce quality of life and life expectancy. This book  reviews the role of cortisol in the human body, focusing on the effects  of excess cortisol due  to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function.  The volume will cover basic mechanistic data, clinical outcomes data,  and novel therapies. Also discussed are everything from abnormalities of  the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and  metabolic disorders, to new definitions of Cushing’s remission and  recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and  Disease will provide a comprehensive and multi-disciplinary review of  the pathophysiology and outcomes of excess cortisol in  the human body and brain as well as the role of the HPA axis in other  disease states.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-12-16\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319459486\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-45950-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 327\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44395555225740,"sku":"9783319459486","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319459486_4d341254-ed3a-4fcf-982e-bf8b635e3e68.jpg?v=1776774247","url":"https:\/\/lateknightbooks.com\/products\/9783319459486","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}