Springer Theses: From Structure to Flux Balances

Güell, Oriol

This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures.

The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions.

Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec

Details

Published by: Springer

Publication Date: 2017-08-24

Format: Hardcover

ISBN-13: 9783319639994

DOI: 10.1007/978-3-319-64000-6

Dimensions: 235cm x155cm

Pages: 151