{"product_id":"9783319817682","title":"The Functional Nucleus","description":"\u003ch1\u003eThe Functional Nucleus\u003c\/h1\u003e \u003ch2\u003eBazett-Jones, David P.; Dellaire, Graham\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis book gives an in-depth overview on nuclear structure and function. It  clearly shows that the epigenome and the three-dimensional organization of the  nucleus are not independent properties. The intimate relationship between the  location and the epigenetic modifications of gene loci is highlighted. Finally,  it shows that the complex three-dimensional organization of the nucleus is not  just of academic interest: The structure, composition and function of virtually  all of the sub-nuclear compartments identified so far can be implicated to a  list of human genetic diseases. Hence, a detailed elucidation of how these  domains are assembled and function will provide new opportunities for  therapeutic intervention in clinical practice.\u003cbr\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-06-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319817682\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-38882-3\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 513\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":46266661535884,"sku":"9783319817682","price":197.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319817682.jpg?v=1770827708","url":"https:\/\/lateknightbooks.com\/products\/9783319817682","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}