{"product_id":"9783319858500","title":"Resistance to Targeted Anti-Cancer Therapeutics","description":"\u003ch1\u003eResistance to Targeted Anti-Cancer Therapeutics\u003c\/h1\u003e \u003ch2\u003eVillanueva, Augusto\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cul\u003e \u003c\/ul\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-08-02\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319858500\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-56197-4\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 147\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44395441389708,"sku":"9783319858500","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319858500.jpg?v=1770822008","url":"https:\/\/lateknightbooks.com\/products\/9783319858500","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}