{"product_id":"9783527329663","title":"Methods \u0026 Principles in Medicinal Chemistry","description":"\u003ch1\u003eMethods \u0026amp; Principles in Medicinal Chemistry\u003c\/h1\u003e\u003ch2\u003e\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eContributors:\u003c\/strong\u003e Gohlke, Holger; Mannhold, Raimund; Kubinyi, Hugo; Folkers, Gerd\u003c\/p\u003e\u003cp\u003eInnovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for\u003cbr\u003e development. \u003cbr\u003e The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here,\u003cbr\u003e as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at\u003cbr\u003e unresolved challenges, and the strategies to address them.\u003cbr\u003e With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of\u003cbr\u003e protein-ligand interaction modeling and analysis for both novices and experts.\u003c\/p\u003e\u003ch3\u003eBook Details\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublisher:\u003c\/strong\u003e Wiley-VCH\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e 2012-05-21\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Hardcover\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eISBN-13:\u003c\/strong\u003e 9783527329663\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePages:\u003c\/strong\u003e 359\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Wiley-VCH","offers":[{"title":"Default Title","offer_id":44314364510348,"sku":"9783527329663","price":179.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783527329663.jpg?v=1768916762","url":"https:\/\/lateknightbooks.com\/products\/9783527329663","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}