Streamlined, cost-effective, and environmentally benign concepts for the synthesis of chemical building blocks and pharmaceuticals

Directed C—H Bond Functionalization summarizes recent advances in the field of selective and efficient C—H bond functionalization using directing groups.

Written by a team of experts in the field, Directed C—H Bond Functionalization includes information on:

• History of the C—H bond activation and its discovery
• In-built functional group-directed C—H functionalization, proximal C—H bond functionalization, and template-assisted distal C—H bond functionalization
• Transient-directing group-assisted C—H bond functionalization and bifunctional non-covalent template-assisted C—H functionalization
• Redox catalytic methods and metal-free directed C—H functionalization reactions
• Industrial and synthetic application of directed C—H bond functionalization in organic synthesis, medicinal, and process chemistry

With its all-encompassing approach, Directed C—H Bond Functionalization is a timely, essential reference for synthetic chemists in academia and industry working in the fields of organic synthesis, catalysis, sustainable chemistry, and drug design.

Debabrata Maiti is Professor and Institute Chair in the Department of Chemistry, IIT Bombay, India. His research interests are focused on the development of new and sustainable synthetic and catalytic methodologies. He is an Associate Editor for the Journal of Organic Chemistry (ACS).

Supriya Rej is a Ramanujan faculty in the Department of Chemistry at IIT Dharwad, India. His current research focuses on bond activation and synthetic methodology development.