This handbook provides a comprehensive overview of Partial Least Squares (PLS) methods with specific reference to their use in marketing and with a discussion of the directions of current research and perspectives. It covers the broad area of PLS methods, from regression to structural equation modeling applications, software and interpretation of results. It features papers on the use and the analysis of latent variables and indicators by means of the PLS path modeling approach from the design of the causal network to model assessment and improvement. Within the PLS framework, the handbook also addresses advanced topics. Most chapters comprise a thorough discussion of applications to marketing and related areas, some tutorials focus on key aspects of PLS analysis with a didactic approach.