This book describes four different methods of paleotemperature assessment on selected Paleozoic rock units and determines spatial variations in maximum burial depths of these units and thicknesses of lost overburden. Stratigraphic and tectonic history of the northern Appalachian basin is described in details followed by a critical review of fluid inclusion, clay diagenesis, organic maturation, and stable isotope techniques of paleotemperature measurements in sedimentary rocks.