This book constitutes the refereed proceedings of the 6th International Conference on Business Process Management, BPM 2008, held in Milan, Italy, in September 2008. The volume contains 20 revised full research papers and 3 industrial papers carefully reviewed and selected from 154 submissions, as well as 8 prototype demonstration papers selected out of 15 demo submissions. In addition three invited keynote papers are presented. The conference has a record of attracting innovative research of the highest quality related to all aspects of BPM, including theory, frameworks, methods, techniques, architectures, standards, and empirical findings.