Drug Design: Methodology, Concepts, and Mode-of-Action

Klebe, Gerhard

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.

Details

Published by: Springer

Publication Date: 2013-07-10

Format: Hardcover

ISBN-13: 9783642179068

DOI: 10.1007/978-3-642-17907-5

Dimensions: 235cm x155cm

Pages: 901