This book constitutes the refereed proceedings of the Second International Conference on ICT as Key Technology for the Fight against Global Warming, ICT-GLOW 2012, held in Vienna, Austria, in September 2012, in conjunction with DEXA 2012. The 9 revised papers presented were carefully reviewed and selected for inclusion in the volume. They are organized in the following topical sections: novel implementations for energy awareness; green data centers and supercomputing; and green organization and business modelling.