{"product_id":"9783642691317","title":"The Origins of Depression: Current Concepts and Approaches: Report of the Dahlem Workshop on The Origins of Depression: Current Concepts and Approaches Berlin 1982, Oct.31 – Nov. 5","description":"\u003ch1\u003eThe Origins of Depression: Current Concepts and Approaches: Report of the Dahlem Workshop on The Origins of Depression: Current Concepts and Approaches Berlin 1982, Oct.31 – Nov. 5\u003c\/h1\u003e \u003ch2\u003eAngst, J.; Angst, J.; Checkley, S.A.; Carlsson, A.; Katschnig, H.; Carroll, B.J.; Potter, W.Z.; Helmchen, H.; Reite, M.L.; Herz, A.; Rush, A.J.; Klerman, G.I.; McKinney, W.T.\u003c\/h2\u003e \u003cp\u003e3 and a fraction mayor may not respond to treatment. On the behavioral level, animal research shows that a variety of experimental conditions can induce de­ pression. The same is true in the field of treatment, where pharmacologically highly different drugs can equally alleviate depression in animals and hu­ mans. The question as to whether this is due to a heterogeneity of depressive subjects based on different pathogenetic mechanisms is open to discussion. We can look for common features of all possible causal factors in the hope of finding a single basic mechanism. Many divergent findings may also be ex­ plained as peripheral changes of a highly complicated dynamic system. In the field of psychopharmacology, a circular reasoning has become evident in the sense that originally the clinical antidepressive response was founded on empirical grounds only. In a second step, an attempt was made to characterize some clinically active compounds pharmacologically, and in a third, further compounds were developed based on aspects of the pharmaco­ logical profiles. Moreover, the post hoc development of a pharmacological screening method has the serious disadvantage of delaying breakthroughs into new fields.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2011-11-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783642691317\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-642-69129-4\u003c\/p\u003e \u003cp\u003eDimensions: 229.0cm x152.0cm\u003c\/p\u003e \u003cp\u003ePages: 474.0\u003c\/p\u003e ","brand":"Springer Berlin Heidelberg","offers":[{"title":"Default Title","offer_id":44448448184460,"sku":"9783642691317","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783642691317.jpg?v=1756867333","url":"https:\/\/lateknightbooks.com\/products\/9783642691317","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}