The Biology of Germinal Centers in Lymphoid Tissue

Thorbecke, G. Jeanette; Tsiagbe, Vincent K.

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.

Details

Published by: Springer

Publication Date: 2013-01-22

Format: Paperback

ISBN-13: 9783662131435

DOI: 10.1007/978-3-662-13141-1

Dimensions: 235cm x155cm

Pages: 241