{"product_id":"9783662667507","title":"Early Trauma as the Origin of Chronic Inflammation: A Psychoneuroimmunological Perspective","description":"\u003ch1\u003eEarly Trauma as the Origin of Chronic Inflammation: A Psychoneuroimmunological Perspective\u003c\/h1\u003e \u003ch2\u003eStraub, Rainer H.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cdiv\u003e\n\u003cdiv\u003eThe aim of the book is to sensitize physicians and researchers to the important long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and basic researcher in psychoneuroimmunology, shows connections between adverse childhood experiences and typical adult sequelae. After early traumatic experiences and childhood stress, there is a higher incidence of mental illness, chronic pain, sleep disorders, dental problems, obesity, cardiovascular disease, asthma, diabetes mellitus and chronic inflammation. A selection of diseases unmistakably demonstrate the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that has a negative effect in adulthood.\u003cbr\u003e \u003c\/div\u003e\n\u003cdiv\u003eFrom his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and are involved in chronic immune activation: direct connectors originating from the brain, indirect connectors functioning through hormonal and neuronal pathways, extracorporeal (the environmental factors) and pleiotropic connectors (genetic factors).\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003eThe translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.\u003cbr\u003e\n\u003c\/div\u003e\u003cdiv\u003e\u003c\/div\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2023-02-03\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783662667507\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-662-66751-4\u003c\/p\u003e \u003cp\u003eDimensions: 240cm x168cm\u003c\/p\u003e \u003cp\u003ePages: 256\u003c\/p\u003e ","brand":"Springer Berlin Heidelberg","offers":[{"title":"Default Title","offer_id":45590079176844,"sku":"9783662667507","price":34.19,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783662667507.jpg?v=1776086818","url":"https:\/\/lateknightbooks.com\/products\/9783662667507","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}