{"product_id":"9784431544593","title":"Testicular Autoimmunity: A Cause of Male Infertility","description":"\u003ch1\u003eTesticular Autoimmunity: A Cause of Male Infertility\u003c\/h1\u003e \u003ch2\u003eItoh, Masahiro\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cdiv\u003eThis book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity.\u003c\/div\u003e\u003cdiv\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003eAccordingly, the book discusses “the immunological fragility of testis” with regard to male infertility, re\u003c\/div\u003e\n\u003c\/div\u003eviewing autopsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. \u003cbr\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003eIn summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.\u003c\/div\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2017-08-14\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9784431544593\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-4-431-54460-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 232\u003c\/p\u003e ","brand":"Springer Japan","offers":[{"title":"Default Title","offer_id":44698777485452,"sku":"9784431544593","price":143.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9784431544593.jpg?v=1779941275","url":"https:\/\/lateknightbooks.com\/products\/9784431544593","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}