{"product_id":"9789400760875","title":"SpringerBriefs in Molecular Science","description":"\u003ch1\u003eSpringerBriefs in Molecular Science\u003c\/h1\u003e \u003ch2\u003eChakraborty, Ranjan; Braun, Volkmar; Hantke, Klaus; Cornelis, Pierre\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eIron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ways to overcome iron deficiency. One of them is producing an iron-chelating small organic molecule called siderophore. Indeed, most bacteria and fungi produce structurally and chemically diverse siderophores which are transported back to the cytoplasm using complex energy dependent transport systems. \u003ci\u003eEscherichia coli\u003c\/i\u003e and \u003ci\u003ePseudomonas\u003c\/i\u003e were the first ones to be tested; however, nowadays iron transport systems have been investigated in many other bacteria. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eIron Uptake in Bacteria with Emphasis on E. coli and\u003c\/i\u003e \u003ci\u003ePseudomonas\u003c\/i\u003e reviews the recent advancements in the field of iron transport systems in bacteria. Chapter 1 is dedicated to Dr. Dick van der Helm’s contribution to the field of siderophore biology. It then describes and discusses the structural advances in the components and the mechanism of siderophore mediated iron transport systems in \u003ci\u003eE.coli\u003c\/i\u003e. Chapter 2 details the variety of iron transport and iron regulatory systems of both gram negative and gram positive bacteria. Finally, chapter 3 describes the iron transport systems of \u003ci\u003ePseudomonas\u003c\/i\u003e. \u003c\/p\u003e\u003cp\u003eThis book is aimed at researchers in the fields of iron metabolism in multiple organisms, and to those who are interested in studying iron transport systems of bacteria. It appeals also to scientists researching structure and function relationship of proteins.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-02-03\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9789400760875\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-94-007-6088-2\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 89\u003c\/p\u003e ","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":47400990539916,"sku":"9789400760875","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789400760875.jpg?v=1775788053","url":"https:\/\/lateknightbooks.com\/products\/9789400760875","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}