{"product_id":"9789401044943","title":"Genetic factors in coronary heart disease","description":"\u003ch1\u003eGenetic factors in coronary heart disease\u003c\/h1\u003e \u003ch2\u003eGoldbourt, U.; de Faire, U.; Berg, K.\u003c\/h2\u003e \u003cp\u003eIncidence and mortality of atherosclerosis and coronary heart  disease (CHD) vary considerably among races, populations and ethnic  groups. Some individuals with low levels of risk factors succumb early  to disease while many others with a high risk profile do not. CHD  clusters in families and is manyfold increased in first degree  relatives of persons with an early onset of the disease. Such studies  provide compelling evidence of the high degree of heritability of CHD  and its risk factors. \u003cbr\u003e  This book consolidates the available evidence for the roles of  genetics in atherosclerosis, its correlates and its sequelae. It  presents and discusses the methodology currently used to elucidate the  role of genetics. Separate parts focus on evidence of familial  aggregation and ethnic variability of the disease and on monogenic and  polygenic inheritance modes including all the recent findings and  innovation. The book also contains chapters on the genetic aspects of  vessel wall processes, such as early structural findings in  histological studies and the variability of coronary anatomic  patterns. Polymorphisms at the DNA level (RFLP) are detailed and  reviewed. Directions for future research in the exciting and fast  developing realm of genetic epidemiology are outlined and the major  preventive and public health implications are discussed. \u003cbr\u003e  \u003cem\u003eGenetic Factors in Coronary Heart Disease\u003c\/em\u003e provides a systematic  review of findings, integrated to offer a comprehensive summary and  stepping stone for future research. It will be of interest to  investigators in atherosclerosis, genetics, epidemiology,  biostatistics, cardiology and public health. \u003cbr\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2012-10-11\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9789401044943\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-94-011-1130-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 463\u003c\/p\u003e ","brand":"Springer","offers":[{"title":"Default Title","offer_id":44398564376716,"sku":"9789401044943","price":198.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789401044943.jpg?v=1755437555","url":"https:\/\/lateknightbooks.com\/products\/9789401044943","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}