Stress Response Pathways in Cancer: From Molecular Targets to Novel Therapeutics

Wondrak, Georg T.

It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel book provides a comprehensive perspective on cell stress response pathways and therapeutic opportunities. Focusing on the role of genotoxic, proteotoxic, oxidative, metabolic, and inflammatory stress in tumorigenesis, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in cancer and therapeutic development.

Details

Published by: Springer

Publication Date: 2016-09-10

Format: Paperback

ISBN-13: 9789402403855

DOI: 10.1007/978-94-017-9421-3

Dimensions: 235cm x155cm

Pages: 446