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Frontiers in Protein Structure, Function, and Dynamics
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Frontiers in Protein Structure, Function, and Dynamics
Singh, Dev Bukhsh; Tripathi, Timir
This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances.
Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.Details
Published by: Springer
Publication Date: 2020-07-03
Format: Hardcover
ISBN-13: 9789811555299
DOI: 10.1007/978-981-15-5530-5
Dimensions: 235.0cm x155.0cm
Pages: 452.0