This book collects papers presented at the International Conference on Mathematical Modelling and Computational Intelligence Techniques (ICMMCIT) 2021, held at the Department of Mathematics, The Gandhigram Rural Institute (Deemed to be University), Gandhigram, Tamil Nadu, India, from 10–12 February 2021. Significant contributions from renowned researchers from fields of applied analysis, mathematical modelling and computing techniques have been received for this conference. Chapters emphasize on the research of computational nature focusing on new algorithms, their analysis and numerical results, as well as applications in physical, biological, social, and behavioural sciences. The accepted papers are organized in topical sections as mathematical modelling, image processing, control theory, graphs and networks, and inventory control.