This book presents the findings of the Endophthalmitis Management Study (EMS), a multicentric randomized control trial conducted in India, focusing on acute endophthalmitis following cataract surgery. It introduces innovative methodologies, including the inflammation score to measure associated inflammation objectively and new molecular technology such as the next-generation sequencing for microbiology work-up. It provides new evidence-based guidance for managing acute endophthalmitis after cataract surgery.

Chapters explore the effectiveness of inflammation-score-based treatment strategies and efficacy of new intravitreal antibiotics. The authors provide an analysis of subgroup data, offering insights into the diverse manifestations of endophthalmitis. It presents an innovative algorithm to measure the infectivity of the condition, while the visual functional study offers crucial information on macular function following successful treatment. 

This essential resource is tailored for vitreo retina specialists and general ophthalmologists, offering them the latest research and practical strategies for managing acute endophthalmitis.

Dr Taraprasad Das, MD, FRCS, DSc, FAMS is the Vice Chairman (Emeritus) of L V Prasad Eye Institute, Hyderabad, India. He is a Fellow of the National Academy of Medical Sciences, India; President-elect of Asia Pacific Academy of Ophthalmology; Fellow of the Academy of Asia-Pacific Professors in Ophthalmology; Fellow, All India Collegium of Ophthalmology; and Chief advisor-mentor of Shantilal Shanghvi Eye Institute, Mumbai. He has published 358 journal papers and written 58 book chapters. He has delivered 28 eponymous lectures. His primary research interests are endophthalmitis, diabetic retinopathy and public health ophthalmology. His recognition includes the Government of India Civil Honour, Padmasri; American Academy of Ophthalmology and Asia Pacific Academy of Ophthalmology Senior Achievement awards; and Vitreo Retinal Society of India and All India Ophthalmological Society lifetime achievement award. In the Stanford University ranking, he is in the top 2% of research scientists in World Ophthalmology.

Dr Vivek P Dave, MD, FRCS is the Head of the Anant Bajaj Retina Institute at L V Prasad Eye Institute (LVPEI) and Adjunct Assistant Professor of Ophthalmology, University of Rochester, NY, USA. He is a Fellow of the International Council of Ophthalmology and a Member of the National Academy of Medical Sciences, India. He is a mentor-faculty for ORBIS CyberSight and the Asia Pacific Academy of Ophthalmology leadership development program. He is an Associate Board Member of the Asia Pacific Academy of Ophthalmology’s Congress Committee, a Board Member of the Asia Pacific Ophthalmic Trauma Society, and a member of the International Society of Ocular Trauma and the Club Jules Gonin. Recognized for his contributions, Dr Dave has received national and international awards from the Uveitis Society of India, the All India Ophthalmological Society, the Vitreoretinal Society of India, the Asia Pacific Academy of Ophthalmology, the Asia Pacific Vitreoretinal Society, and the Vitreoretinal Society of India. Dr Dave has 177 peer-reviewed scientific international research publications.

Dr. Joveeta Joseph, PhD, is the Head of the Jhaveri Microbiology Centre and Microbiology Services across the L V Prasad Eye Institute (LVPEI) network, Hyderabad, India. She is a medical microbiologist with expertise in endophthalmitis, ocular microbiology, molecular diagnostics, antimicrobial resistance, and host–pathogen interactions. Her research integrates genomics, transcriptomics, proteomics, and other multi-omics approaches to improve the understanding, diagnosis, and management of infectious endophthalmitis and other ocular infections. She has published over 190 peer-reviewed journal articles and authored eight book chapters. She serves as Associate Editor of Frontiers in Immunology, Frontiers in Cellular and Infection Microbiology, and BMC Ophthalmology; Academic Editor of PLOS ONE; and is a member of the Editorial Board of the Indian Journal of Ophthalmology.  Dr. Joseph serves on the Annual Meeting Program Committee of the Association for Research in Vision and Ophthalmology (ARVO) for the Immunology and Microbiology Section and chaired the committee during 2025–2026. She was selected for the ARVO Women's Leadership Development Program (2023–2024) and participated in the ARVO Global Mentorship Program in 2022 and 2023. Additionally, she serves as a member of the American Society for Microbiology (ASM) Global Outreach Program.