This book introduces in detail the development of traditional and novel vaccines, covering key technologies, principles, and current progress, while providing a comprehensive overview of genes, genomes, genetic markers, and sequencing technologies, together with advances in human genome research, particularly genetic diversity. It further explains how genomic technologies enable vaccine development based on pathogen genomics and human genetic variation, including HLA diversity, and outlines current progress and future directions in this field. It is suitable for researchers, clinicians, and postgraduate students in vaccinology, genomics, and related biomedical sciences.

Dr. Jiayou Chu is a researcher, doctoral supervisor and professor at the Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College. He has been engaged in genetic and molecular biology research，vaccinology research and clinical work in hematology and oncology for more than 30 years. He is the chief leader of the project "Preservation of genomes of different ethnic groups in China and study of genetic diversity" in the Chinese Human Genome Project. Dr. Chu has published more than 200 science papers.