This book introduces the principles, materials, methods, and applications of biofabrication and bioprinting for tissue engineering and regenerative medicine. It examines the design, fabrication, and functionalization of biological constructs using advanced manufacturing techniques, with emphasis on the interactions between cells, biomaterials, scaffold architecture, and fabrication processes.

The book covers biofabrication techniques, tissue engineering fundamentals, computational design and modelling of scaffolds, extrusion-based bioprinting, cell-laden bioinks, hydrogels, polymers, multi-material printing, and mechanical and biological characterization. Applications include three-dimensional models of orthopaedic, skin, muscle, and tumour tissues, organs-on-a-chip, wound healing, surgical simulation, and implantable devices.

Further topics include vascularization, biocompatibility, scalability, clinical translation, and regulatory considerations, as well as emerging areas such as 4D bioprinting, smart materials, and sensor-integrated bioengineered constructs. The book also considers the economic and environmental aspects of biofabrication.

The book is intended for graduate students, researchers, and professionals working in biofabrication, bioprinting, tissue engineering, regenerative medicine, biomedical engineering, and biomaterials science.

Prof. Arnab Chanda is an Associate Professor in the Centre for Biomedical Engineering, Indian Institute of Technology (IIT) Delhi, and a joint faculty at the Department of Biomedical Engineering, AIIMS, Delhi. He is also the founder of a start-up company BIOFIT Technologies LLC, USA. He received his PhD from the University of Alabama, USA and has also been a Postdoctoral Researcher at the University of Pittsburgh, USA. Dr. Chanda specializes in the area of Biomechanics and Biomaterials, especially in Tissue Mimicking (Artificial Tissues) and Characterization, finite element modeling (FEM), robotics and wearable device development, and entrepreneurship. He has received Young Researcher Award and Early Career Award from ASME, MHRD, and AO Spine International-Singapore, and also holds Top-Cited Paper Awards. He holds and has filed 10+ US and Indian Patents, authored several Books and 100+ articles in various international journals. He currently serves as the Associate Editor for the Journal of Appl. Biomaterials & Func. Materials, Associate Editor for the Frontiers in Medical Engineering, Editorial board member for Nature Scientific Reports, and as the guest editor for several journals such as Engineering Research Express.

Dishant Sharma is a Mechanical Engineering graduate from Maharishi Dayanand University, Rohtak, with a foundation in design, manufacturing, and computational modeling. He has developed hands-on experience through training and industry exposure in areas such as quality inspection, production engineering, and 3D design, including work with tools like SolidWorks. Dishant has worked at the Centre for Biomedical Engineering at the Indian Institute of Technology (IIT) Delhi, where he has been involved in interdisciplinary research focused on biofabrication, bioprinting technologies, and the development of artificial tissues. His work includes contributing to engineering design and modeling aspects relevant to scaffold fabrication and tissue engineering applications, aligning with emerging advances in regenerative medicine.