This 2-volume set CCIS 2778+2779 constitutes the proceedings of the Third International Conference on Applied Intelligence, ICAI 2025, held in Nanning, China, during November 6–9, 2025.

The 70 full papers presented in this proceedings were carefully selected and reviewed from 289 submissions. 

They were organized in topical sections as follows: 

Part I: Image Processing; Knowledge Discovery and Data Mining; Machine Learning; Pattern Recognition.

Part II: Biomedical Data Modeling and Mining; Neural Networks; Pattern Recognition.