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Drug Absorption Studies

Drug Absorption Studies In Situ, In Vitro and In Silico Models

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Biotechnology: Pharmaceutical Aspects

Drug Absorption Studies

In Situ, In Vitro and In Silico Models

Carsten Ehrhardt | Kwang-Jin Kim

Medical / Pharmacology

Ideal material for a huge range of professionals in drug therapeutics and research, this is a well thought-out, highly practical text covering contemporary ‘in vitro’ techniques for drug absorption studies. Starting at the molecular level of investigation, it continues with cell monolayer models (both primary and cell lines) and culminates with in situ techniques as a final testing format. In addition, chapters on high-throughput assays, in vitro-in vivo correlation, bioinformatics and regulatory issues are covered, giving a comprehensive overview of available models and techniques. Moreover, an appendix consisting of a number of practical protocols is available online, updated as needed, and should prove very helpful to apply the techniques directly to the benchside.


Publication Date: 18 January 2008
Publisher: Springer US
Imprint: Springer
ISBN-13: 9780387749006
Format: Hardback
Page Count: 696

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