Principles of Process Research and Chemical Development in the Pharmaceutical Industry

Repic, Oljan

This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.

Details

Published by: Wiley-Interscience

Publication Date: 1998-01-05

Format: Hardcover

ISBN-13: 9780471165163

DOI:

Dimensions: 240.5cm x161.5cm

Pages: 240.0