Chemical Intolerance identifies phenolic (aromatic) chemical compounds present in natural foodstuffs, pollens, certain food additives, tobacco smoke, perfumes, air pollution, etc., as nonimmunologic, but pharmacologic activators of allergic reactions in chemically intolerant individuals. Biochemical pathway sequences, with supporting scientific literature, are outlined to elucidate the mechanisms associated with formation of inflammatory mediators (prostaglandins, thromboxanes, and leukotrienes) upon activation by phenolic compounds and other chemical stimulants. The role of these inflammatory agents in respiratory, gastrointestinal, neurological, cardiovascular, and other disorders is discussed. Treatment modalities using precise dosages of selected phenolic compounds are outlined to provide clinicians with an effective means of therapy. The author also shares his own experience and personal findings based on 20 years of research, including his recommendations for therapy.

Robert W. Gardner, Ph.D., is Professor Emeritus of Animal Science at Brigham Young University, Provo, Utah. Dr. Gardner was a member of the University Research Committee and the Faculty Advisory Council of Brigham Young University; he served for many years as guest editor of the Journal of Applied Physiology; and he has been invited to present a variety of papers throughout his career as a consultant, teaching professor, and research scientist.