This book provides a comprehensive overview of cutting-edge research and breakthroughs in the field of nanotherapeutics, offering an in-depth analysis of a wide array of strategies, materials used, and applications. The introductory chapter establishes a foundational understanding of nanomedicine, elucidating its principles and its transformative potential in therapy. Subsequent chapters delve into advanced strategies for precision medicine, encompassing both passive and active targeting approaches. The book discusses stimuli-responsive therapies, explores peptide-based targeting, examines antibody-driven nanotherapeutics, and highlights the remarkable progress achieved in the realm of cancer nanotherapeutics. It reveals the immense potential of nanobiosensors for early cancer detection, thereby laying the groundwork for the development of next-generation diagnostics and monitoring tools. Additionally, it thoroughly scrutinizes the role of nanomaterials in biomedical imaging, with a particular emphasis on the application of lanthanide-based nanomaterials in fluorescent imaging and theranostics. The book also serves as a bridge between traditional herbal remedies and modern medicine by investigating the integration of medicinal plants into the field of nanomedicine. Finally, it addresses the critical issue of nanotoxicology, providing readers with a comprehensive overview of the challenges and future prospects associated with ensuring the safety of nanomaterials in medical applications. This book is mainly intended for researchers, scholars, and students of nanotechnology, biotechnology, and medical research and it can also serve as a teaching tool for bionanotechnology students.

Key features

· Covers a wide range of therapeutic approaches in nanomedicine, including both passive and active targeting strategies.

· Explores design and development of various nanoformulations such as liposomal designs, silica nanoparticles, and polymer-based nanoformulations, and their biomedical applications.

· Discusses development of nanobiosensors for cancer detection and the use of nanomaterials in biomedical imaging.

· Explores controlled release of anticancer drugs, engineered nanofibers, and formulations that have reached clinical trials.

· Examines use of antibodies in nanotherapeutics, addressing current challenges and future directions in this field.

· Addresses the critical aspects of nanotoxicology, offering a comprehensive overview of the safety challenges.

Mushtaq A. Beigh is currently serving as a Senior Assistant Professor in the Department of Nanotechnology at the University of Kashmir, India. Previously, Dr. Beigh held multiple postdoctoral fellowships such as Young Scientist fellow (SERB) and DBT-Research Associate for carrying out research on mTOR cell signaling. He completed his PhD in Growth Factor Signaling Laboratory at the Department of Biotechnology, University of Kashmir, India. Presently, he leads the Cellular Signaling and Nanotherapeutics Laboratory at the University of Kashmir. His team is focused on understanding the molecular mechanisms of cancer metastasis and developing nanomaterial-based drug conjugates for targeted cancer therapies. Dr. Beigh has numerous international and national publications to his credit.

Shafquat Majeed currently holds the position of Senior Assistant Professor in the Department of Nanotechnology at the University of Kashmir, India. He earned his master’s degree in Chemistry from the Department of Chemistry at the University of Kashmir and completed his PhD at Indian Institute of Science, Bangalore. His postdoctoral research, conducted at the Centre for Nanoscience and Engineering, IISc Bangalore, from 2015 to 2016, focused on rare-earth-based nanomaterials for biomedical applications and the fabrication of perovskite-based solar cells. Presently, Dr. Majeed leads the Multifunctional Nanomaterials Laboratory at the University of Kashmir. His research group specializes in the synthesis, characterization, and investigation of the optical, magnetic and catalytic properties of nanomaterials and MOFs prepared through various solution-based routes.