This detailed volume aims to serve researchers working in antibody-drug conjugate (ADC) development by guiding them through the entire process, from payload selection to QA/QC design for regulatory approval, while also providing a deeper understanding of the various stages of ADC evolution. While the rapid pace of technological advancements continues to reshape the ADC landscape, this book covers the foundational principles, key milestones, and the latest cutting-edge methodologies, presented by experts in the field. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.

Authoritative and practical, Antibody-Drug Conjugates (ADCs): Methods and Protocols is a valuable resource for designing and accelerating ADC development programs, inspiring and empowering scientists to further innovate in this field, ultimately contributing to the advancement of more effective and safer therapies.