Cellular Senescence and Tumor Suppression

Adams, Peter D.; Sedivy, John M.

As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.

Details

Published by: Springer

Publication Date: 2009-12-17

Format: Hardcover

ISBN-13: 9781441910745

DOI: 10.1007/978-1-4419-1075-2

Dimensions: 235cm x155cm

Pages: 272