Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine

Mattson, Mark P.

Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.

Details

Published by: Humana

Publication Date: 2004-10-22

Format: Hardcover

ISBN-13: 9781588293541

DOI: 10.1385/159259803X

Dimensions: 235cm x155cm

Pages: 214