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Spaceflight and the Central Nervous System

Spaceflight and the Central Nervous System Clinical and Scientific Aspects

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Spaceflight and the Central Nervous System

Clinical and Scientific Aspects

Alex P. Michael | Christian Otto | Millard F. Reschke | Alan R. Hargens

Medical / Neurology

This book consolidates the current knowledge of how short and long-duration spaceflight affects the anatomy and physiology of the central nervous system. It also incorporates the methodology and constraints of studying the central nervous system in space. 

Chapters detail advances in imaging techniques available to assess intracranial and intraocular pathology as well as translational medicine with an emphasis on brain cancer and neurodegenerative disease in spaceflight. Additionally, the book offers theoretical background information, tested laboratory protocols, and step-by-step methods for reproducible lab experiments to aid neuroscientists and neurobiologists in laboratory testing and experimentation. 

Spaceflight and the Central Nervous System is the first to comprehensively include all aspects of spaceflight-induced changes in the central nervous system. It is an invaluable resource for basic and clinical laboratory trainees and researchers in aerospace medicine and physiology or for those looking to gain specific knowledge in spaceflight neuroscience.
Alex P. Michael, MD

Neurological Surgeon, Mercy Clinic Neurosurgery


Christian Otto, MD
Director of Teleoncology, Memorial Sloan Kettering Cancer Center
Former Lead Scientist for NASA’s Visual Impairment Intracranial Pressure Risk Group

Alan R. Hargens
Department of Orthopaedic Surgery
University of California
San Diego, CA

Millard F. Reschke

Johnson Space Center

NASA Neuroscience

Houston, TX



Publication Date: 29 December 2022
Publisher: Springer International Publishing
Imprint: Springer
ISBN-13: 9783031184390
Format: Hardback
Page Count: 140

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