This book constitutes the refereed proceedings of the 17th International Conference on Learning and Intelligent Optimization, LION-17, held in Nice, France, during June 4–8, 2023.

The 40 full papers presented have been carefully reviewed and selected from 83 submissions. They focus on all aspects of unleashing the potential of integrating machine learning and optimization approaches, including automatic heuristic selection, intelligent restart strategies, predict-then-optimize, Bayesian optimization, and learning to optimize.