Uniquely, neural stem cells reside in the dentate gyrus of the hippocampus, the gateway to memory formation. They give rise to new neurons that incorporate in the hippocampal circuitry and play pivotal roles in learning and memory in the mammalian brain. In Hippocampal Neurogenesis, Fred Gage, Orly Lazarov and a cadre of top authorities discuss the latest evidence and leader perspectives on this fascinating phenomenon and its implications for brain function in health, disease, and specifically dementia.

Fred H. Gage, PhD, is Professor in the Laboratory of Genetics, and the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Diseases, the Salk Institute for Biologic Studies, La Jolla, California

Orly Lazarov, PhD, is Professor of Neuroscience in the Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois