This book provides a detailed overview of the latest advancements in regenerative medicine for degenerative spine conditions to manage the chronic pain caused by these degenerative diseases. Edited and authored by globally recognized experts in the field, this comprehensive resource bridges critical knowledge gaps, offering insights into the latest advancements and techniques, including stem cell therapy, platelet rich plasma, orthobiologics, and tissue engineering. It explores the existing evidence, ethical considerations, and the future directions of regenerative spine and chronic pain medicine, including nanotechnology, bioprinting, and artificial intelligence. 

Dr. Abd-Elsayed is the Medical Director of UW Health Pain Services, Medical Director of UW pain Clinic, Division Chief of Chronic Pain Medicine, and Associate Professor of Anaesthesiology at the University of Wisconsin, Madison, Wisconsin, USA. He has published over 320 peer reviewed manuscripts, edited over 30 books, written over 300 book chapters and has served on the editorial board of several journals.

Dr. Sudhir Diwan, nationally and internationally recognized as a key opinion leader in the field of pain management, is the President, Advanced Spine on Park Avenue, and attending at Lenox Hill Hospital, New York. Dr. Diwan was the former Director of the Tri-Institutional Pain Fellowship Program and Division of Pain Medicine at Ivy League Weill Medical College of Cornell University for more than a decade, where he also served as associate professor of clinical anesthesiology, and the faculty at the world renowned New York Presbyterian Hospital. Dr. Diwan has published extensively in prestigious peer-reviewed medical journals and medical books on a variety of pain management topics. He is on the Editorial Board for the journals of Pain Physician, Pain Practice, and Pain Research. Dr. Diwan is the Examiner for the Certification Board for American Board of Interventional Pain Physicians (ABIPP) and Fellow of Interventional Pain Practice (FIPP).

Dr. Diwan is recipient of many accolades including Trailblazer award (2023) by WIP, Lifetime Achievements Award by ASIPP (2022), Lifetime Global Educator Award by NYNJ Pain Congress (2022) Raj Excellence Award by ASIPP (2021), Lifetime Achievements award by American Society of Pain and Neuroscience (ASPN - 2020), League of Presidents Award by ASIPP (2020), Distinguished Service award by ASIPP (2017), Clinical excellence award by WVSIPP (2013), and Outstanding Contribution to Pain Management award by NYSIPP (2013). Dr. Diwan lectures extensively and interacts regularly with experts in the field of Minimally Invasive Spinal Procedures, Neuromodulation, and Regenerative Medicine nationally and internationally.  He has been guest speaker for many noteworthy organizations including the American Society of Interventional Pain Physicians (ASIPP), American Society of Pain and Neuroscience (ASPN), the World Institute of Pain (WIP). Currently he is Executive Director of NYSIPP and Course Chairman of the Annual NYNJ Pain Congress and Chairman of Latin American Pain Society (LAPS). He is on executive boards of ASIPP as Director Emeritus.

Dr. Annu Navani is the Chief Medical Officer at Reve Health Institute, where she leads advanced regenerative and longevity medicine programs integrating precision medicine, cellular regeneration, and age-optimization science. A board-certified specialist in Pain and Regenerative Medicine, she is also the Founder of the World Institute of Regenerative Medicine (WIRM), and the President of the American Society of Interventional Pain Physicians (ASIPP). In academia, Dr. Navani has served for over two decades as Adjunct Clinical Faculty at Stanford University, and also serves as Chief Medical officer of Boomerang Healthcare. Dr. Navani has been recognized with multiple honors, including the Outstanding Achievement Awards from various national and international professional organizations and has published extensively including several national clinical guidelines, and books. Widely regarded as an influencer and authority in emerging medical technologies, Dr. Navani’s expertise spans digital health, applied biologics, and innovation in global healthcare systems, where she continues to shape the future of regenerative and longevity medicine.

Douglas P. Beall, MD, attended medical school at Georgetown University School of Medicine in Washington, DC, and completed his residency at The Johns Hopkins Hospital in Baltimore, Maryland, and a fellowship in Musculoskeletal Radiology at Mayo Clinic in Rochester, Minnesota before entering the US Air Force as Division Chief of Musculoskeletal Radiology. Following his service as a Major in the US Air Force Dr. Beall was chief of Musculoskeletal Radiology and Fellowship Director at the University of Oklahoma prior to entering private practice as the Chief of Services. He is board-certified in Diagnostic Radiology, has an added fellowship in Musculoskeletal Radiology, is a Diplomate of the American Academy of Pain Management and is a Fellow of the Society of Interventional Radiology, the American Society of Interventional Pain Physicians, the American Society of Spine Radiology and a Fellow of Interventional Pain Practice and board certified by the World Institute of Pain. He is currently in private practice focused on interventional pain management and orthopedic imaging.