Apply chemical engineering principles to biological processes with confidence

Biochemical Engineering: A Textbook for Engineers, Chemists and Biologists, now in its Third Edition, delivers a structured approach to applying chemical engineering principles to biological systems. Written by a team of experienced biochemical engineers from leading Japanese universities, this textbook requires no prior chemical engineering knowledge while building the analytical skills needed to solve real bioprocess problems.

The Third Edition adds a new chapter on monoclonal antibodies and therapeutic proteins, covering upstream processing, downstream purification, and quality control. The three-part structure progresses from fundamental concepts through process aspects like heat transfer, mass transfer, and bioreactors, to practical applications including fermentor engineering and medical device production. More than one hundred exercises support self-study.

The book includes:

• Clear explanations connecting fundamental engineering principles to therapeutic protein production, bridging classical biochemical engineering with modern industrial biotechnology
• Comprehensive coverage of bioseparation methods, bioreactor design, bioprocess control, and biorecognition assays essential for bioprocess development
• Over one hundred exercises with detailed questions and answers enabling students to build strong fundamentals through structured self-study
• New coverage of monoclonal antibody production including upstream processing, downstream purification, quality control methods, and future industry perspectives
• Logical three-part organization progressing from basic concepts through process aspects to practical applications without requiring prior engineering background

Undergraduate students in biotechnology, chemical engineering, and biology will find this textbook builds essential bioprocess engineering competencies systematically. Lecturers at universities and applied sciences institutions gain a proven resource that connects theory to industrial practice across food, pharmaceutical, and water treatment applications.

Shigeo Katoh is Professor Emeritus at Kobe University, Japan, and former Head of the Bioengineering Laboratory. He has served as full professor at Hanyang University in Korea and visiting professor at Cheng Kung University in Taiwan, publishing extensively in biochemical engineering.

Jun-ichi Horiuchi, PhD, is Director of the Instrumental Analysis Center at the Kitami Institute of Technology since 2010. He holds a doctorate in biotechnology from the Science University of Tokyo and previously worked as a research engineer at Toyo Engineering Corporation.

Fumitake Yoshida is Professor Emeritus of chemical engineering at Kyoto University. He was elected to the National Academy of Engineering of the United States in 1979 for leadership in chemical, biochemical, and biomedical engineering in Japan.

Yoichi Kumada is a specialist in bioseparation engineering at the Kyoto Institute of Technology. His research focuses on bioseparation engineering, affinity chromatography, and antibody engineering, with advanced degrees from Kobe University.