This book constitutes the refereed proceedings of the 5th INNS IAPR TC3 GIRPR International Workshop on Artificial Neural Networks in Pattern Recognition, ANNPR 2012, held in Trento, Italy, in September 2012. The 21 revised full papers presented were carefully reviewed and selected for inclusion in this volume. They cover a large range of topics in the field of neural network- and machine learning-based pattern recognition presenting and discussing the latest research, results, and ideas in these areas.