A Handbook of Transcription Factors

Hughes, Timothy R.

Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes.  In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. 

This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Details

Published by: Springer

Publication Date: 2013-07-15

Format: Paperback

ISBN-13: 9789400736047

DOI: 10.1007/978-90-481-9069-0

Dimensions: 235.0cm x155.0cm

Pages: 306.0