This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs.

In this second edition, the contents are updated according to the rapid development of molecular detection and diagnostic technology. 10 chapters are added, such as CTC and ctDNA detection, description and verification of biological reference intervals, and molecular diagnosis in 4 more common clinical diseases. It lets readers to understand and realize precision healthcare.

Editor Shiyang Pan, M.D, Ph.D., is a chief physician and the director of the Dept. of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Editor Jinhai Tang is a professor at The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.