The third edition of this atlas provides an updated overview of histopathology across all organ systems, incorporating the latest developments in diagnostic pathology. This edition features over 3,500 high-quality illustrations; it also covers the 5th and where applicable 6th edition of the World Health Organization (WHO) classifications of tumors for each organ system and discusses the up-to-date diagnostic criteria, including the use of ancillary and molecular tests that have become the standard of care for MMR, KRAS, HER2, and BRAF testing in colorectal cancer, and EGFR, ROS1, and ALK testing in non-small cell lung cancer. Additionally, the diagnosis of brain tumors, which now requires multiple immunohistochemistry (IHC) and molecular-based tests as standard practice, is addressed, together with updated guidance on predictive pathology, including commonly used biomarkers such as ER, PR, PD-L1, and HER2, as well as an introduction to next-generation sequencing (NGS). The atlas is further supplemented with easy-to-understand images, selected radiologic correlations where relevant, and interpretive guidelines for ancillary reflex testing to support accurate diagnosis and clinical decision-making.
This atlas is relevant for trainees in histopathology, anatomic pathology, and cellular pathology, as well as surgical and practicing pathologists. It is also a valuable reference for physicians, radiologists, biomedical scientists, and other healthcare professionals involved in diagnostic pathology.

Dr. Shahid Pervez, MBBS, DCP (Lon), PhD (Histopathology, Lon), FCPS (CPSP, Pakistan), FRCPath (UK), MIAC, is a professor and senior consultant histopathologist at the Aga Khan University Hospital, Karachi, Pakistan. His clinical, diagnostic, and research interests include hematopathology, head and neck pathology, and predictive pathology. Dr. Pervez has authored more than 270 peer-reviewed publications in national and international journals, contributed to several book chapters, and served as an international adviser for the renowned textbook Underwood's Pathology. He is Head of Pathology at the College of Physicians and Surgeons Pakistan (CPSP), editor of CPSP official medical journals i.e., JCPSP and JCPSP-PG, and also serves as the lead examiner and convener for postgraduate Histopathology exit examinations. A recognized leader in pathology, Dr. Pervez has held numerous national and international leadership roles. He is the Country Advisor and Memorandum of Understanding (MoU) signatory for the Royal College of Pathologists, UK. He is the founder and current President of the International Academy of Pathology (IAP)–Pakistan Division and currently serves as Secretary of the Assembly of Asia Pacific International Academy of Pathology (AAPIAP). He also founded the Histopathology and Cytology Society of Pakistan (HCSP) and the South Asian Academy of Cytology and Histopathology (SACH) and is the immediate Past President of the Pakistan Association of Pathologists (PAP). In addition, Dr. Pervez has served as chair of the Karachi Cancer Registry for over a decade and is Co-Chair of the National Cancer Registry, contributing significantly to cancer surveillance and pathology practice in Pakistan.